At Glendale Whole Health, our Metabolic Reset Program goes beyond appetite suppression and traditional weight-loss programs. We combine physician-guided medical therapy with metabolic testing, body composition analysis, required laboratory evaluation, nutrition support and functional medicine strategies to help patients lose weight in a healthier, more sustainable way.
Our program includes injectable and oral GLP-1 options including semaglutide, also known as Ozempic®/Wegovy®, tirzepatide, also known as Mounjaro®/Zepbound®, retatrutide and orforglipron, also known as Foundayo™, when clinically appropriate.
Unlike online GLP-1 programs that may provide medication without deeper metabolic guidance, we focus on healthy fat loss with minimal loss of muscle mass. Our goal is to help patients improve body composition, preserve metabolic rate, avoid "Ozempic face" or "Ozempic butt" and sustain long-term success.
Our Functional Medicine Approach
Weight loss is not the same as metabolic health.
At Glendale Whole Health, we evaluate and address the underlying factors that commonly contribute to weight gain, cravings, inflammation and metabolic dysfunction including:
- Insulin resistance
- Blood sugar imbalance
- Hormonal changes including testosterone, estrogen, progesterone and thyroid dysfunction
- Stress and cortisol imbalance
- Sleep disruption
- Gut health and digestion
- Nutrient deficiencies
- Loss of lean muscle mass
- Difficulty efficiently burning fat and regulating energy (poor metabolic flexibility)
- Detoxification and toxin support during fat loss
Our goal is not simply a lower number on the scale. Our goal is healthier body composition, better energy, improved metabolic health and sustainable long-term results.
Helpful related services:
Healthy Weight Loss & Muscle Preservation
One of the most important goals of our program is preserving metabolically active lean muscle while reducing excess body fat.
Skeletal muscle is one of the body’s major sites for glucose disposal and plays a key role in insulin sensitivity, metabolic rate, strength, mobility and healthy aging. When weight loss occurs too quickly or without enough protein, resistance training and metabolic support, patients may lose too much muscle along with fat.
This can contribute to:
- Lower resting metabolic rate
- Increased risk of weight regain
- "Skinny fat" body composition
- Fatigue and weakness
- Loss of firmness in the face or body
- The appearance often described as "Ozempic face" or "Ozempic butt"
Our program emphasizes:
- Body Composition Analysis
- Resting Metabolic Rate Testing
- Adequate protein intake
- Resistance training and movement
- Thoughtful medication dosing
- Functional medicine lab evaluation
- Muscle-supportive peptide options when appropriate
Initial Consultation & Metabolic Assessment
Your program begins with a comprehensive medical consultation with Dr. Speller.
This includes:
- Comprehensive medical consultation
- Review of goals and weight-loss history
- Metabolic RMR Testing
- Body Composition Analysis
- Personalized treatment planning
- Discussion of medication and dosing options
- Functional medicine evaluation
- Review recent labs or order a comprehensive set of personalized labs
Required Laboratory Assessment
Because Glendale Whole Health practices functional metabolic medicine, baseline laboratory testing is required for all patients entering the program.
Labs help identify underlying contributors to:
- Weight gain
- Insulin resistance
- Inflammation
- Hormonal imbalance
- Thyroid dysfunction
- Fatigue and cravings
- Cardiovascular risk
- Nutrient deficiencies
- Poor metabolic function
Patients may use recent outside labs if they were completed within the past 3 months and are adequate for clinical decision making. Additional testing may still be recommended to achieve a more comprehensive metabolic and functional medicine assessment.
Patients may also choose:
- Insurance-based laboratory testing when applicable
- Cash-pay functional medicine laboratory testing
Our comprehensive cash-pay report includes a visually organized, easy-to-understand functional medicine summary. This report includes system-based scoring and visual summaries across areas such as metabolic health, hormones, nutrition, cardiovascular health, immune health, gut health, musculoskeletal health and energy health.
Nutritional & Lifestyle Support
Medication works best when paired with education, structure and healthier metabolic habits.
Patients in our program receive guidance on:
- Protein optimization
- Blood sugar balance
- Appetite regulation
- Intermittent fasting strategies
- Meal timing
- Exercise and movement
- Muscle preservation during weight loss
- Long-term maintenance strategies
Clean Start Weight Loss® Patient Guide
Patients in our program receive the Clean Start Weight Loss® Patient Guide, a medically supervised ketogenic and intermittent fasting guide designed to support structured nutrition and metabolic reset.
The guide includes:
- Nutrition education
- Meal planning strategies
- Label-reading guidance
- Exercise recommendations
- Weight-loss tracking tools
- Recipes and lifestyle support
Our goal is not temporary weight loss. Our goal is helping patients develop healthier long-term metabolic habits.
Monthly Membership
$150/month Membership Includes:
- One physician follow-up monthly
- Two Skinny Shots monthly
- Medication monitoring
- Dose adjustment support
- Nutrition and lifestyle guidance
- Side effect support
- Body composition focused guidance
What Are Skinny Shots?
Skinny Shots include B12 and MIC, a combination of the amino acids methionine, inositol and choline. These nutrients are commonly used to support energy, fat metabolism, liver function and healthy methylation during weight-loss programs.
Skinny Shots may be:
- Administered in office
- Dispensed for home administration when appropriate
GLP-1 Medication Options
Injectable GLP-1 Options
Injectable GLP-1 medications currently remain the most established and effective options for significant weight loss and metabolic improvement. Because they bypass gastrointestinal digestion and absorption limitations, injectable therapies may provide stronger and more consistent effects for many patients.
Semaglutide (Ozempic® / Wegovy®)
Semaglutide is a GLP-1 receptor agonist that helps regulate appetite, satiety and blood sugar.
May be ideal for:
- Moderate weight-loss goals
- Insulin resistance
- Prediabetes
- Patients wanting a well-established option
- Microdosing or maintenance support when appropriate
Pricing: $200/month
Tirzepatide (Mounjaro® / Zepbound®)
Tirzepatide activates both GLP-1 and GIP pathways and may provide stronger appetite suppression and metabolic effects compared to semaglutide.
May be ideal for:
- Stronger appetite control
- More significant weight-loss goals
- Greater insulin resistance
- Patients who plateau on semaglutide
- Microdosing or maintenance support when appropriate
Pricing: $300/month
Retatrutide
Retatrutide is an advanced next-generation metabolic peptide that activates GLP-1, GIP and glucagon receptors.
Retatrutide is currently investigational and not commercially FDA-approved. It may be considered only in select cases when clinically appropriate.
This triple-action mechanism may support:
- Greater fat loss
- Increased metabolic activity
- Improved insulin sensitivity
- More advanced body composition changes
Retatrutide may be appropriate for:
- Advanced metabolic dysfunction
- Patients who plateau on semaglutide or tirzepatide
- Patients seeking more aggressive metabolic support
Pricing starts at $450/month and varies based on individualized dosing protocols
Oral GLP-1 Options
For patients who prefer to avoid injections, oral GLP-1 medications may offer a convenient alternative for appetite regulation and metabolic support.
Oral Semaglutide (Rybelsus®)
Rybelsus® is an oral form of semaglutide that may be appropriate for select patients seeking a non-injectable GLP-1 option. Because it contains semaglutide, it works similarly to Ozempic® and Wegovy® by supporting appetite regulation, satiety and blood sugar balance.
Rybelsus® may be appropriate for patients who:
- Prefer oral medication
- Are hesitant about injections
- Travel frequently
- Want a lower-barrier introduction to GLP-1 therapy
Unlike injectable semaglutide, Rybelsus® must be taken on an empty stomach with specific administration instructions for proper absorption. Rybelsus® is commercially manufactured and not available as a compounded medication.
Pricing starts at $149/month through manufacturer or pharmacy programs
Orforglipron (Foundayo™)
Foundayo™ is Eli Lilly’s new oral GLP-1 medication. This may be a good option for patients who:
- Prefer not to inject
- Travel frequently
- Want easier storage and administration
- Are interested in a daily oral option
Unlike oral semaglutide (Rybelsus®), orforglipron is a non-peptide GLP-1 medication and does not require the same strict absorption instructions. It may be taken more flexibly without fasting requirements or prolonged waiting before meals. Foundayo™ is commercially manufactured and available only through approved manufacturer/pharmacy channels.
Pricing starts at $149/month through manufacturer programs
GLP-1 Comparison Chart
| Medication | Brand Names | Pathways | Approximate Weight Loss in Major Studies | Best For |
|---|---|---|---|---|
| Semaglutide | Ozempic® / Wegovy® | GLP-1 | ~15% | Established option, moderate weight loss, insulin resistance, microdosing |
| Tirzepatide | Mounjaro® / Zepbound® | GLP-1 + GIP | ~20% | Stronger appetite control, greater metabolic support, patients who plateau on semaglutide |
| Retatrutide | Investigational | GLP-1 + GIP + Glucagon | ~24% | Advanced metabolic dysfunction, greater weight-loss potential, plateau support |
| Oral Semaglutide | Rybelsus® | Oral GLP-1 | ~10% | Patients preferring a non-injectable semaglutide option |
| Orforglipron | Foundayo™ | Oral GLP-1 | ~11% | Patients wanting a flexible non-peptide oral GLP-1 option |
Commercial Dosing vs Customized Dosing
Not every patient needs the highest dose.
At Glendale Whole Health, we offer both:
- Commercial pharmacy dosing protocols
- Customized or compounded non-commercial dosing strategies when appropriate
Depending on the patient, we may use:
- Slower titration schedules
- Lower-dose protocols
- Intermediate dosing adjustments
- Microdosing approaches
- Individualized escalation strategies
This allows treatment to be tailored to side effect tolerance, appetite response, weight-loss goals, body composition goals and metabolic health.
Microdosing & Metabolic Optimization
Not all patients require full therapeutic GLP-1 dosing.
For select patients, lower-dose semaglutide or tirzepatide protocols may be used to support:
- Appetite regulation
- Craving reduction
- Metabolic flexibility
- Reduced inflammation
- Longevity and healthy aging
- Body composition maintenance
Microdosing may be appropriate for:
- Normal weight patients
- Mildly overweight patients
- Maintenance patients
- Metabolically healthy individuals
- Patients sensitive to side effects
- Those seeking a gentler approach
Our microdosing philosophy focuses on individualized metabolic support rather than aggressive appetite suppression. Pricing for microdosing is the same as standard dosing.
Optional Add-Ons & Metabolic Support
Patients enrolled in the Glendale Whole Health Metabolic Reset Program receive 10% off the following selected services while actively enrolled in the program:
- Select Peptide Therapies
- Skinny Shots and Elite Skinny Shots
- CGM add-ons
- Detoxification Programs & Kits
- Select Injection and IV Therapy Services
At Glendale Whole Health, we offer multiple metabolic optimization tools to help personalize treatment, improve body composition, support energy and maximize long-term success throughout your weight-loss journey.
Continuous Glucose Monitor (CGM)
A 2-week Continuous Glucose Monitor is available for $60 before member discount.
A CGM allows patients to see how food, stress, sleep and exercise affect blood sugar in real time.
Especially helpful for:
- Insulin resistance
- Prediabetes
- Cravings
- Weight-loss plateaus
- Metabolic optimization
Peptide Enhancements
Peptides are short chains of amino acids that act as signaling molecules within the body. Certain peptides may support appetite regulation, body composition, muscle preservation, recovery and metabolic health.
Learn more about our Peptide Therapy Options.
AOD-9604 — Commonly used to support fat metabolism, stubborn fat reduction and body composition optimization, especially abdominal fat. It may be especially helpful for patients who plateau during GLP-1 therapy or want additional support targeting excess body fat while preserving lean muscle.
Cagrilintide — A long-acting amylin analog peptide. Amylin is a natural hormone released by the pancreas alongside insulin that helps regulate fullness and satiety after eating. Cagrilintide may be especially helpful for reducing food noise, improving fullness signaling and supporting appetite control. It may be especially useful in combination with semaglutide or tirzepatide for patients who need additional satiety support or who have plateaued on standard GLP-1 therapy.
CJC-1295 / Ipamorelin — May support lean muscle preservation, improved body composition, recovery and sleep, healthy aging and metabolic support during weight loss.
Vitamin Injection Enhancements
Learn more about our Injection and IV Therapy Menu.
Skinny Shots: B12 + MIC — Two Skinny Shots are included monthly with membership. Additional Skinny Shots may be purchased for patients who want weekly injections or extra support between visits. Available in office or take home when appropriate.
Elite Skinny Shot: B12 + MIC + L-Carnitine — Our Elite Skinny Shot includes B12, MIC and L-carnitine. L-carnitine helps transport fatty acids into the mitochondria where they can be used for energy. It supports fat metabolism, exercise performance, mitochondrial function and body composition goals. Elite Skinny Shots may be used as an upgrade or purchased separately.
Taurine Injections — Taurine supports metabolic health, cellular hydration, cardiovascular function, exercise recovery and insulin sensitivity.
Alpha Lipoic Acid Injections — An antioxidant involved in mitochondrial energy production and glucose metabolism. May support insulin sensitivity, oxidative stress balance and metabolic health.
Vitamin Infusion Support (IV Drips)
Select IV infusions also qualify for the program member discount and may help support hydration, energy, nutrient status, recovery and metabolic function during weight loss.
Learn more about our Injection and IV Therapy Menu.
Weight Loss Infusion — Myers’ + MIC + L-Carnitine + Taurine. Supports fat metabolism, energy production, mitochondrial support, exercise recovery and body composition goals.
Energy Boost Infusion — Myers’ + Double B Complex. Supports energy, focus, stamina and nutrient replenishment.
Hydration Infusion — Normal Saline. Supports hydration, recovery, electrolyte balance and wellness during appetite suppression or reduced oral intake.
Classic Myers’ Cocktail — Supports energy, stress resilience, nutrient optimization and general wellness and recovery.
What Makes Glendale Whole Health Different?
Unlike many online GLP-1 programs, we provide:
- Physician-guided care with Dr. Speller
- Functional metabolic medicine
- Required lab evaluation
- RMR testing
- Body composition analysis
- Muscle-preservation focused strategies
- Commercial and customized dosing options
- Injectable and oral GLP-1 options
- Microdosing and maintenance protocols
- Skinny Shots included with membership
- Optional peptide enhancement therapies
- Optional CGM tracking
- Detoxification and metabolic support options
- IV and injection support options
- Nutritional education and metabolic lifestyle support
- Long-term metabolic support
Frequently Asked Questions
What is the GLP-1 Metabolic Reset Program?
Our Metabolic Reset Program combines physician-guided GLP-1 therapy with metabolic testing, body composition analysis, required laboratory evaluation and functional medicine strategies. Unlike standard weight-loss programs, we focus on healthy fat loss with minimal muscle loss, improved body composition and sustainable long-term results.
Who is a good candidate for this program?
This program may be appropriate for adults who are overweight or obese, have insulin resistance or prediabetes, struggle with cravings or appetite control, have plateaued with diet and exercise alone, or are interested in metabolic health optimization. A consultation with Dr. Speller is required to determine candidacy.
What GLP-1 medications are available?
We offer injectable options including semaglutide (Ozempic®/Wegovy®), tirzepatide (Mounjaro®/Zepbound®) and retatrutide, as well as oral options including oral semaglutide (Rybelsus®) and orforglipron (Foundayo™). The most appropriate option is determined during your consultation.
Is laboratory testing required?
Yes. Baseline laboratory testing is required for all patients entering the program. Labs help identify underlying contributors to weight gain, insulin resistance, inflammation, hormonal imbalance and metabolic dysfunction. Patients may use recent outside labs completed within the past 3 months if clinically adequate.
What does the monthly membership include?
The $150/month membership includes one physician follow-up visit monthly, two Skinny Shots monthly, medication monitoring, dose adjustment support, nutrition and lifestyle guidance, side effect support and body composition focused guidance. GLP-1 medication is priced separately.
What are Skinny Shots?
Skinny Shots include B12 and MIC (methionine, inositol and choline). These nutrients are commonly used to support energy, fat metabolism, liver function and healthy methylation during weight-loss programs. Two Skinny Shots are included with monthly membership.
Do you offer microdosing?
Yes. For select patients, lower-dose semaglutide or tirzepatide protocols may be used to support appetite regulation, craving reduction, metabolic flexibility and body composition maintenance. Microdosing is available at the same price as standard dosing.
How do I get started?
Call us at (818) 551-0464 or email info@glendalewholehealth.com to schedule your initial consultation with Dr. Speller.
Schedule Your Consultation
If you’re ready to explore GLP-1 weight loss therapy with semaglutide, tirzepatide, retatrutide or Foundayo™, call us at (818) 551-0464 or email info@glendalewholehealth.com to request an appointment.
At Glendale Whole Health we’ll design a personalized plan that fits your goals and supports long-term success.